The calculated distance (air line) between Ramstein-Miesenbach and Karlsruhe is approximately 49 miles respectively 78 kilometers.
By car or train, the actual journey to Karlsruhe is certainly longer, as only the direct route (as the crow flies) between Ramstein-Miesenbach and Karlsruhe has been calculated here.
Air line (approximately)
78 kilometers
42 nautical miles