The calculated distance (air line) between Neustadt an der Aisch and Wiesbaden is approximately 111 miles respectively 178 kilometers.
By car or train, the actual journey to Wiesbaden is certainly longer, as only the direct route (as the crow flies) between Neustadt an der Aisch and Wiesbaden has been calculated here.
Air line (approximately)
178 kilometers
96 nautical miles