The calculated distance (air line) between Karlsruhe and Neustadt an der Aisch is approximately 107 miles respectively 172 kilometers.
By car or train, the actual journey to Neustadt an der Aisch is certainly longer, as only the direct route (as the crow flies) between Karlsruhe and Neustadt an der Aisch has been calculated here.
Air line (approximately)
172 kilometers
93 nautical miles