The calculated distance (air line) between Karlsruhe and Neumarkt in der Oberpfalz is approximately 139 miles respectively 224 kilometers.
By car or train, the actual journey to Neumarkt in der Oberpfalz is certainly longer, as only the direct route (as the crow flies) between Karlsruhe and Neumarkt in der Oberpfalz has been calculated here.
Air line (approximately)
224 kilometers
121 nautical miles