The calculated distance (air line) between Karlsruhe and Neuhaus am Rennweg is approximately 160 miles respectively 258 kilometers.
By car or train, the actual journey to Neuhaus am Rennweg is certainly longer, as only the direct route (as the crow flies) between Karlsruhe and Neuhaus am Rennweg has been calculated here.
Air line (approximately)
258 kilometers
139 nautical miles