The calculated distance (air line) between Clausthal-Zellerfeld and Wuppertal is approximately 142 miles respectively 229 kilometers.
By car or train, the actual journey to Wuppertal is certainly longer, as only the direct route (as the crow flies) between Clausthal-Zellerfeld and Wuppertal has been calculated here.
Air line (approximately)
229 kilometers
124 nautical miles