The calculated distance (air line) between Biberach an der Riß and Karlsruhe is approximately 90 miles respectively 144 kilometers.
By car or train, the actual journey to Karlsruhe is certainly longer, as only the direct route (as the crow flies) between Biberach an der Riß and Karlsruhe has been calculated here.
Air line (approximately)
144 kilometers
78 nautical miles