The calculated distance (air line) between Tauberbischofsheim and Wuppertal is approximately 158 miles respectively 254 kilometers.
By car or train, the actual journey to Wuppertal is certainly longer, as only the direct route (as the crow flies) between Tauberbischofsheim and Wuppertal has been calculated here.
Air line (approximately)
254 kilometers
137 nautical miles