The calculated distance (air line) between Tauberbischofsheim and Karlsruhe is approximately 71 miles respectively 114 kilometers.
By car or train, the actual journey to Karlsruhe is certainly longer, as only the direct route (as the crow flies) between Tauberbischofsheim and Karlsruhe has been calculated here.
Air line (approximately)
114 kilometers
62 nautical miles