The calculated distance (air line) between Heppenheim an der Bergstrasse and Düsseldorf is approximately 136 miles respectively 219 kilometers.
By car or train, the actual journey to Düsseldorf is certainly longer, as only the direct route (as the crow flies) between Heppenheim an der Bergstrasse and Düsseldorf has been calculated here.
Air line (approximately)
219 kilometers
118 nautical miles