The calculated distance (air line) between Enkenbach-Alsenborn and Wuppertal is approximately 127 miles respectively 204 kilometers.
By car or train, the actual journey to Wuppertal is certainly longer, as only the direct route (as the crow flies) between Enkenbach-Alsenborn and Wuppertal has been calculated here.
Air line (approximately)
204 kilometers
110 nautical miles