The calculated distance (air line) between Enkenbach-Alsenborn and Karlsruhe is approximately 40 miles respectively 64 kilometers.
By car or train, the actual journey to Karlsruhe is certainly longer, as only the direct route (as the crow flies) between Enkenbach-Alsenborn and Karlsruhe has been calculated here.
Air line (approximately)
64 kilometers
35 nautical miles