The calculated distance (air line) between Saltburn-by-the-Sea and Milton Keynes is approximately 176 miles respectively 283 kilometers.
By car or train, the actual journey to Milton Keynes is certainly longer, as only the direct route (as the crow flies) between Saltburn-by-the-Sea and Milton Keynes has been calculated here.
Air line (approximately)
283 kilometers
153 nautical miles