The calculated distance (air line) between Stoke-on-Trent and Middlesbrough is approximately 115 miles respectively 186 kilometers.
By car or train, the actual journey to Middlesbrough is certainly longer, as only the direct route (as the crow flies) between Stoke-on-Trent and Middlesbrough has been calculated here.
Air line (approximately)
186 kilometers
100 nautical miles